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Best Translational Medicines Service in India

OVERVIEWTranslational medicine, also known as translational cancer medicine, is a multidisciplinary approach that aims to improve the treatment response, survival rates, and quality of life of cancer patients. It involves transforming scientific discoveries into clinical applications. One of the crucial roles of translational medicine is to identify and study genetic abnormalities that cause cancers. This research provides oncologists with a better understanding of the disease, allowing them to develop efficient treatment protocols.

By making cancer care more targeted and personalised, translational medicine has led to the development of new anti-cancer medicines and targeted therapy protocols that have shown improved efficacy and reduced toxicity. As a result, it has a positive impact on the patient's recovery and quality of life.

Translational Medicine at HCG

Translational Medicine is driven by our patients, their diseases, and a quest to ethically do more than available Evidence-Based Medicine. It is a disruptive, yet systematic endeavour guided by a primary focus towards translational sciences spanning across the spectrum of molecular and cell biology to preclinical models to patient studies and back again, following the principles of critical path analysis and a six-sigma framework.

The Department of Translational Medicine and Therapeutics is equipped with an early-phase clinical trial centre, preclinical study capabilities, regulatory expertise, a clinical trial network, medical & scientific writing team and oncology analytics capabilities and works closely with genomic researchers and clinical scientists.

Vision

HCG's TMT department is a Centre of Excellence that accelerates oncology research and improves patient treatments and outcomes using a collaborative approach, from bench to bedside and vice-versa.

Mission

TMT at HCG aims to establish a sustainable research enterprise for outcome-based research. It offers cost-effective clinical and non-clinical development services, putting HCG on the world map of oncology research.

Functioning

The department supports all the in-house basic and clinical translational research and has an international second opinion network for patient benefit worldwide. Apart from the in-house research activities the department functions as an interface with the Pharma-Biotech industry and makes HCG their preferred partner in oncology drug development programs across the product life cycles. The department has developed a close relationship with the "Indian Society for Clinical Research (ISCR)" as an Accredited Member Organisation of the society.

Below listed are our focus areas:

Translational oncology – solid tumours and haemato-oncology


Immuno-oncology


Precision immunotherapy


Cell-based therapies


Microbiome interactions


Tumour microenvironment interactions


Translational pathology and digital pathology


Genomic theragnostics (genotype-guided cancer therapy)


Diagnostics development and drug screening


Cancer infections


Preventive oncology, community engagement and population science


Integrative oncology


Regenerative medicine


The Department of Translational Medicine (TMT) provides services that promote a vibrant translational research and training environment at HCG.

Translational Medicine Services

Early-phase Clinical Research Unit (CRU)


Early-phase oncology study design and data management


Internal and international second opinion solutions with a deep scientific dive into rare and recurrent cases


Investigator-initiated studies / real-world research


In-vitro and in-vivo non-clinical proof of concept studies/pharmacology studies


Biomarker research


Regulatory guidance and support


Scientific due diligence


Clinical data analysis


Medical and scientific writing


Research education and workforce development